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With many of the common neurodegenerative diseases, it is clear that single gene mutations account for some proportion of all cases while the rest are ‘sporadic’ in nature.
This leads to the concept that genetic variants, acting within the context of the aging central nervous system and stochastic factors, leads to overall risk of disease.
By explicitly defining trepanation as a form of care, we can use Tilley’s bioarchaeology of care framework to reconstruct the logic of healing.